AWAKEN THE SOUL
Entheogenic Offerings AHAL Clinic Mexico
DMT Assisted Therapy in Mexico
Unlocking Mental Health Solutions
Psychedelic therapy with the assistance of DMT presents an innovative approach to address a range of mental health issues that have become unfortunately commonplace in 21st-century living. Preliminary trials are exploring the potential of DMT-assisted therapy in alleviating depression. The procedure involves a patient consuming a controlled dose of the psychedelic substance DMT under the guidance of a psychotherapist, within the framework of traditional talk therapies. Although research in this domain is in its early stages, there are initial signs suggesting that DMT-assisted therapy might offer substantial benefits to the global population grappling with mental health challenges.
What is DMT?
Dimethyltryptamine, abbreviated as DMT, is a fast-acting psychoactive compound that occurs naturally. It is found in various plants and animals, including humans, and can also be produced synthetically.
From a chemical standpoint, DMT belongs to the tryptamine family of indole alkaloids. It shares a chemical structure with serotonin, the neurotransmitter associated with happiness, wellbeing, and sleep. Additionally, it bears a resemblance to “classic” psychedelic substances like psilocybin and LSD.
Similar to these psychedelics, DMT interacts with various receptors in the brain, notably the 5-HT2A serotonin receptor. This interaction can alter visual perception, interoception (mind processing of bodily sensations), and the individual’s experience of reality during the drug’s brief effects, typically lasting 20-30 minutes. This short duration sets DMT apart from longer-acting psychedelics like LSD or psilocybin, introducing potential for new clinical applications.
Why is DMT sparking scientific interest?
DMT has played a role in cultural rituals across diverse societies for centuries. For instance, it serves as the primary psychoactive component in ayahuasca, a sacred concoction used in ceremonies by the Quechua people in South America.
Like other psychedelic treatments such as LSD, psilocybin, MDMA, and ketamine, DMT is gaining serious scientific attention as a potential treatment for depression. Clinical trials have vouched for the safety and efficacy of various psychedelic substances. While DMT research is still emerging, recent Phase I trials by Small Pharma on healthy volunteers without prior psychedelic experience suggest the drug is well-tolerated. Ongoing Phase II trials focus on assessing its efficacy in treating Major Depressive Disorder.
What is the DMT experience like?
Given the inherent subjectivity of individual perceptions, describing the specific effects of DMT is challenging. However, common themes emerge. Patients often report visual hallucinations, out-of-body experiences, and a sense of being in the presence of an “entity” or a benevolent force. These experiences frequently have a strong autobiographical element, aiding patients in gaining insights previously elusive to them.
Research suggests that DMT may modulate or disrupt neural processes associated with “internalizing” disorders like depression and addiction. Individuals trapped in negative thought patterns may find a way out, making them more receptive to therapy and enabling fresh perspectives.
What role does therapy play?
In DMT-assisted therapy, the therapeutic aspect is as crucial as the DMT component. Treatment should occur in a controlled setting under the guidance of a trained psychotherapist. The therapist establishes trust, prepares the patient, sets intentions, remains present during the DMT experience, and engages in integration therapy afterward. This approach helps patients interpret their experiences, leverage new insights, and break free from negative patterns.
How do people respond to DMT?
Phase I trials on 32 healthy volunteers show that DMT has a favorable safety and tolerability profile compared to other medicines. Some participants in other DMT trials reported mildly elevated heart rate and blood pressure, with a few describing the experience as “unpleasant” or “dysphoric.” These risks can be influenced by dosing and proper patient support.
How does DMT compare with other psychedelics?
Recent Phase I trials by Small Pharma, the first certified trials on DMT for major depressive disorders, establish its safety. Comparative studies between DMT-assisted therapy and other psychedelic treatments are still in their early stages. According to the Global Drugs Survey, DMT, compared to LSD, psilocybin, and ketamine, is rated highest for “strength of pleasure,” lowest for “negative effects while high,” “risk of harm,” and “come down after use.”
Is the DMT experience intense?
DMT is considered more immersive than LSD or psilocybin but over a much shorter duration. A typical DMT experience lasts less than 30 minutes, while psilocybin effects can extend over several hours. Individuals under DMT often describe transcending their body, communicating with entities, experiencing temporary loss of self (ego-dissolution), contemplating death, and feeling love and connection. While intense, understanding and therapist sensitivity can mitigate concerns, with intensity potentially contributing to long-term therapeutic benefits.
Is DMT the same as ayahuasca?
Not exactly. DMT is the primary psychoactive component in ayahuasca, but differences exist between controlled DMT doses in therapy and consuming an ayahuasca brew in ceremonial settings. Ayahuasca, a blend of Psychotria viridis and Baniteriospsis caapi, lasts much longer orally, while dosing uncertainties, organizer trustworthiness, and overall legality pose challenges.
What about 5-Meo-DMT?
5-Meo-DMT, sometimes known as “toad,” is distinct from DMT. While it belongs to the same tryptamine family, it is derived from the secretions of the Bufo Alvarius toad. Although related, they are not identical substances.
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